NPR3 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of NPR3.
Immunogen
A synthetic peptide corresponding to amino acids 520-533 at C-terminus of human NPR3.
Sequence
C-HRELREDSIRSHFS
Host
Goat
Theoretical MW (kDa)
52
Reactivity
Human
Specificity
The immunizing peptide represents the cytoplasmic part of the protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
NPR3 polyclonal antibody (Cat # PAB24575) (1 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NPR3
Entrez GeneID
4883Protein Accession#
NP_000899.1Gene Name
NPR3
Gene Alias
ANPRC, GUCY2B, NPRC
Gene Description
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Omim ID
108962Gene Ontology
HyperlinkGene Summary
The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM
Other Designations
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