NPR3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with NPR3 polyclonal antibody (Cat # PAB31160) shows strong cytoplasmic positivity in leydig cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human NPR3.
Immunogen
Recombinant protein corresponding to human NPR3.
Sequence
GFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with NPR3 polyclonal antibody (Cat # PAB31160) shows strong cytoplasmic positivity in leydig cells. -
Gene Info — NPR3
Entrez GeneID
4883Protein Accession#
P17342Gene Name
NPR3
Gene Alias
ANPRC, GUCY2B, NPRC
Gene Description
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Omim ID
108962Gene Ontology
HyperlinkGene Summary
The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM
Other Designations
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Interactome
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Disease
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Publication Reference
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Molecular subgroups of medulloblastoma: the current consensus.
Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SM.
Acta Neuropathologica 2012 Apr; 123(4):465.
Application：IHC, Human, Human medulloblastoma tissues.
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Molecular subgroups of medulloblastoma: the current consensus.
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