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Last updated: 2016/10/23
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CTCFL polyclonal antibody

  • Catalog # : PAB20061
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant CTCFL.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human CTCFL.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human testis with CTCFL polyclonal antibody (Cat # PAB20061) shows strong nuclear positivity in primary spermatocytes.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line U-251 MG with CTCFL polyclonal antibody (Cat # PAB20061) at 1-4 ug/mL dilution shows positivity in nucleus, cytoplasm.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • Gene Alias:
  • BORIS,CTCF-T,MGC163358,dJ579F20.2
  • Gene Description:
  • CCCTC-binding factor (zinc finger protein)-like
  • Gene Summary:
  • CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. [provided by RefSeq
  • Other Designations:
  • BORIS-like protein,CCCTC-binding factor-like protein,OTTHUMP00000174287,brother of the regulator of imprinted sites
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