Western blot analysis of tissue and whole cell extracts with CAPN1 polyclonal antibody (Cat # PAB19099). Lane 1 : rat brain. Lane 2 : rat heart. Lane 3 : rat testis. Lane 4 : rat thymus. Lane 5 : MM231. Lane 6 : HeLa. Lane 7 : SMMC. Lane 8 : HT1080. Lane 9 : Colo 320 HSR.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. [provided by RefSeq
calcium-activated neutral proteinase,calpain 1, large subunit,calpain, large polypeptide L1,cell proliferation-inducing protein 30