PTP4A2 polyclonal antibody

Catalog # PAB18892

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Size:100 ug
Price: USD $ 346.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of formalin-fixed paraffin-embedded human prostate carcinoma tissue showing cytoplasmic and membrane staining with PTP4A2 polyclonal antibody (Cat # PAB18892) at 1 : 100 dilution.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against partial recombinant PTP4A2.

    Immunogen

    Recombinant protein corresponding to amino acids 2-167 of human PTP4A2.

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Recommend Usage

    ELISA (1:10000-1:80000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In buffer containing 0.02% sodium azide

    Storage Instruction

    Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of formalin-fixed paraffin-embedded human prostate carcinoma tissue showing cytoplasmic and membrane staining with PTP4A2 polyclonal antibody (Cat # PAB18892) at 1 : 100 dilution.

    Enzyme-linked Immunoabsorbent Assay

  • Gene Info — PTP4A2

    Entrez GeneID

    8073

    Protein Accession#

    AF208850

    Gene Name

    PTP4A2

    Gene Alias

    HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A, PTPCAAX2, ptp-IV1a, ptp-IV1b

    Gene Description

    protein tyrosine phosphatase type IVA, member 2

    Omim ID

    601584

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq

    Other Designations

    OTTHUMP00000003902|phosphatase of regenerating liver 2|protein tyrosine phosphatase IVA|protein tyrosine phosphatase IVA2

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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