PTP4A2 monoclonal antibody, clone 5B6F4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) PTP4A2-hIgGFc transfected HEK293 cell lysate with PTP4A2 monoclonal antibody.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of PTP4A2 monoclonal antibody, clone 5B6F4.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human PTP4A2.
Immunogen
Recombinant protein corresponding to amino acids 58-162 of human PTP4A2 from E. coli.
Host
Mouse
Theoretical MW (kDa)
19.1
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry
Immunocytochemistry
Immunohistochemistry
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) PTP4A2-hIgGFc transfected HEK293 cell lysate with PTP4A2 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of PTP4A2 monoclonal antibody, clone 5B6F4. -
Gene Info — PTP4A2
Entrez GeneID
8073Gene Name
PTP4A2
Gene Alias
HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A, PTPCAAX2, ptp-IV1a, ptp-IV1b
Gene Description
protein tyrosine phosphatase type IVA, member 2
Omim ID
601584Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000003902|phosphatase of regenerating liver 2|protein tyrosine phosphatase IVA|protein tyrosine phosphatase IVA2
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