PTP4A2 recombinant monoclonal antibody, clone R02-1H6
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: HeLa whole cell lysate, Lane 2: A549 whole cell lysate and Lane 3: HL-60 whole cell lysate with PTP4A2 recombinant monoclonal antibody, clone R02-1H6 (Cat # RAB04460).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PTP4A2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PTP4A2.
Theoretical MW (kDa)
Calculated MW: 19 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: HeLa whole cell lysate, Lane 2: A549 whole cell lysate and Lane 3: HL-60 whole cell lysate with PTP4A2 recombinant monoclonal antibody, clone R02-1H6 (Cat # RAB04460).Immunoprecipitation
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Gene Info — PTP4A2
Entrez GeneID
8073Protein Accession#
Q12974Gene Name
PTP4A2
Gene Alias
HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A, PTPCAAX2, ptp-IV1a, ptp-IV1b
Gene Description
protein tyrosine phosphatase type IVA, member 2
Omim ID
601584Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000003902|phosphatase of regenerating liver 2|protein tyrosine phosphatase IVA|protein tyrosine phosphatase IVA2
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