LAIR1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of LAIR1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human LAIR1.
Sequence
C-NDTEDVSQASPSE
Host
Goat
Theoretical MW (kDa)
28
Reactivity
Human
Specificity
This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
LAIR1 polyclonal antibody (Cat # PAB18564) (2 ug/mL) staining of human lymph node lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — LAIR1
Entrez GeneID
3903Protein Accession#
NP_002278.1;NP_068352.1Gene Name
LAIR1
Gene Alias
CD305, LAIR-1
Gene Description
leukocyte-associated immunoglobulin-like receptor 1
Omim ID
602992Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq
Other Designations
leukocyte-associated Ig-like receptor 1
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