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PDHA1 (phospho S293) polyclonal antibody (DyLight 488)

  • Catalog # : PAB15341
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDHA1.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S293 human PDHA1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This is specific to the phosphorylated Serine 293 form of the PDHE1 alpha protein. This antibody is useful for Western blot, where a band is seen ~43 KDa.
  • Form:
  • Liquid
  • Conjugation:
  • DyLight 488
  • Recommend Usage:
  • Western Blot (1:2500-1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium borate
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5160
  • Gene Name:
  • PDHA1
  • Gene Alias:
  • PDHA,PDHCE1A,PHE1A
  • Gene Description:
  • pyruvate dehydrogenase (lipoamide) alpha 1
  • Gene Summary:
  • The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000023015,pyruvate dehydrogenase E1 alpha subunit
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