FEZ1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 polyclonal antibody (Cat # PAB13004) at 1 ug/mL in the (A) presence and (B) absence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FEZ1.
Immunogen
A synthetic peptide corresponding to C-terminus 19 amino acids of human FEZ1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 polyclonal antibody (Cat # PAB13004) at 1 ug/mL in the (A) presence and (B) absence of blocking peptide. -
Gene Info — FEZ1
Entrez GeneID
9638Protein Accession#
Q99689Gene Name
FEZ1
Gene Alias
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Gene Description
fasciculation and elongation protein zeta 1 (zygin I)
Omim ID
604825Gene Ontology
HyperlinkGene Summary
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq
Other Designations
zygin 1
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Interactome
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Disease
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Publication Reference
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Two binding partners cooperate to activate the molecular motor Kinesin-1.
Blasius TL, Cai D, Jih GT, Toret CP, Verhey KJ.
The Journal of Cell Biology 2007 Jan; 176(1):11.
Application：IF, Monkey, COS cells.
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Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein.
Kuroda S, Nakagawa N, Tokunaga C, Tatematsu K, Tanizawa K.
The Journal of Cell Biology 1999 Feb; 144(3):403.
Application：WB-Ce, Rat, PC-12 cells.
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The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.
Chien CT, Bartel PL, Sternglanz R, Fields S.
PNAS 1991 Nov; 88(21):9578.
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Two binding partners cooperate to activate the molecular motor Kinesin-1.
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