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Last updated: 2016/12/4
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RPS6KB1 polyclonal antibody

  • Catalog # : PAB12720
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human RPS6KB1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 70
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes ~70 KDa of human RPS6KB1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The cell lysate derived from NIH/3T3 cells was immunoprobed by RPS6KB1 polyclonal antibody (Cat # PAB12720) at 1 : 500.
    An immunoreactive band is observed around ~70kDa (Lane 1).
    This band is blocked by pre-incubation with immunizing peptide (Lane 2).
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6198
  • Gene Name:
  • RPS6KB1
  • Gene Alias:
  • PS6K,S6K,S6K1,STK14A,p70(S6K)-alpha,p70-S6K,p70-alpha
  • Gene Description:
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq
  • Other Designations:
  • p70 S6 kinase, alpha 1,p70 S6 kinase, alpha 2,ribosomal protein S6 kinase, 70kD, polypeptide 1,serine/threonine kinase 14 alpha
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