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Last updated: 2017/11/19
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CASP9 polyclonal antibody

  • Catalog # : PAB0248
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against full length recombinant CASP9.
  • Immunogen:
  • Recombinant protein corresponding to full length human CASP9.
  • Host:
  • Rabbit
  • Reactivity:
  • Dog, Gerbils, Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of CASP9. Various tissue lysates were prepared from human autopsy material and normalized for total protein. Most tissues contained the ~50 KDa pro-CASP9 protein. Cleaved CASP9 was identified in brain cortex and peripheral nerve tissue samples. Pro-C9 : recombinant human pro-CASP9 (full-length) protein. PRO : pro-CASP9. L : large subunit of cleaved CASP9. S : small subunit of cleaved CASP9.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of CASP9 expression in formalin-fixed, paraffin-embedded mouse brain tissue sections. Using CASP9 polyclonal antibody (Cat # PAB0248) at 1 : 2000. Hematoxylin-eosin counterstain. A : Brain striatum. B : Brain stem motor neuron.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 842
  • Gene Name:
  • CASP9
  • Gene Alias:
  • APAF-3,APAF3,CASPASE-9c,ICE-LAP6,MCH6
  • Gene Description:
  • caspase 9, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 6,OTTHUMP00000002322,OTTHUMP00000002323,OTTHUMP00000044594,apoptotic protease MCH-6,apoptotic protease activating factor 3,caspase 9,caspase 9, apoptosis-related cysteine protease
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