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Last updated: 2016/12/4
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ZAP70 monoclonal antibody, clone SBZAP (HRP)

  • Catalog # : MAB5890
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ZAP70.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 280-309 of human ZAP70.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • human TCR ζ; Zap-70 (Mr 70 KDa).
  • Form:
  • Liquid
  • Conjugation:
  • HRP
  • Concentration:
  • Lot specific
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • ELISA (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol)
  • Storage Instruction:
  • Store in the dark at 4°C. For long term storage store at -20°C.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • ELISA
  • Flow Cytometry
  • Application Image
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7535
  • Gene Name:
  • ZAP70
  • Gene Alias:
  • FLJ17670,FLJ17679,SRK,STD,TZK,ZAP-70
  • Gene Description:
  • zeta-chain (TCR) associated protein kinase 70kDa
  • Gene Summary:
  • This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • syk-related tyrosine kinase,zeta-chain (TCR) associated protein kinase (70 kD),zeta-chain associated protein kinase 70kDa,zeta-chain associated protein kinase, 70kD
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