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Last updated: 2017/9/17
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C5AR1 monoclonal antibody, clone S5/1

  • Catalog # : MAB5330
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of C5AR1.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus extracellular domain (met1-Asn31) of human C5AR1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the Nterminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognize the heptameric peptide (D15DKDTLD21). Clone S5/1 has been shown to inhibit the binding of C5a to its receptor. Serotec recommend the use of the monoclonal antibody for functional studies. Cross reacts with human.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (10 ul of the suggested dilution (1:50-1:100) to label 5 x 105 cells in 100 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 728
  • Gene Name:
  • C5AR1
  • Gene Alias:
  • C5A,C5AR,C5R1,CD88
  • Gene Description:
  • complement component 5a receptor 1
  • Other Designations:
  • C5a anaphylatoxin receptor,C5a ligand,complement component 5 receptor 1
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