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Last updated: 2016/12/4
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TNFRSF21 monoclonal antibody, clone Luke-1

  • Catalog # : MAB3436
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against recombinant TNFRSF21.
  • Immunogen:
  • Recombinant Fc fusion protein corresponding to amino acids 42-335 of human TNFRSF21.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes human DR6.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid coding for the extracellular domain of human TNFRSF21 (thick line). Cells (5 X 105) were incubated on ice for 30 min in 50 uL FACS buffer (PBS, 5% FCS, 0.02% sodium azide) containing 1 ug/mL of TNFRSF21 monoclonal antibody, clone Luke-1 (Cat # MAB3436).
  • Application Image
  • Gene Information
  • Gene Name:
  • TNFRSF21
  • Gene Alias:
  • BM-018,DR6,MGC31965
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 21
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016561,OTTHUMP00000039915,TNFR-related death receptor 6,death receptor 6
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