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Last updated: 2016/12/4
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ADRBK1 monoclonal antibody, clone 5D5

  • Catalog # : MAB2373
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant ADRBK1.
  • Immunogen:
  • Recombinant protein corresponding to human ADRBK1.
  • Host:
  • Mouse
  • Reactivity:
  • Bovine, Human, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Immunohistochemistry (1:100)
    Western Blot (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry
  • ADRBK1 monoclonal antibody, clone 5D5 (Cat # MAB2373) (green) and neurofilament NF-M (red) staining, in rat cortex, showing mostly large pyramidal neurons. Photo courtesy of Dr. Gerry Shaw, University of Florida.
  • Immunocytochemistry
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 156
  • Gene Name:
  • ADRBK1
  • Gene Alias:
  • BARK1,BETA-ARK1,FLJ16718,GRK2
  • Gene Description:
  • adrenergic, beta, receptor kinase 1
  • Gene Summary:
  • The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq
  • Other Designations:
  • beta adrenergic receptor kinase 1
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