CDH6 monoclonal antibody, clone AFCE-3
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Jurkat cell lysate; Lane 2: Mouse heart lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CDH6.
Immunogen
A synthetic peptide corresponding to human CDH6.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
The antibody reacts with human, mouse CDH6, in native form and recombinant. Superfamily members of CDH6 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Jurkat cell lysate; Lane 2: Mouse heart lysate.Immunoprecipitation
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Gene Info — CDH6
Entrez GeneID
1004Protein Accession#
P55285Gene Name
CDH6
Gene Alias
KCAD
Gene Description
cadherin 6, type 2, K-cadherin (fetal kidney)
Omim ID
603007Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq
Other Designations
K-cadherin|cadherin 6, K-cadherin (fetal kidney)|cadherin 6, type 2|cadherin, fetal kidney|kidney cadherin
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