Rabbit monoclonal antibody raised against synthetic protein of human DDX5.
Immunogen:
A synthetic peptide corresponding to human DDX5.
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Specificity:
This antibody reacts with human, mouse, rat DDX5, in native form and recombinant. Superfamily members of DDX5 are not reactive to antibody.
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Flow Cytometry (1:50) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200) Immunofluorescence (1:50-200) Immunocytochemistry (1:50-200) Immunoprecipitation (1:50) Western Blot (1:1000-5000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified. [provided by RefSeq