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Last updated: 2021/6/13

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DNMT3A monoclonal antibody, clone PCRP-DNMT3A-1E2 

  • Catalog # : MAB20913
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human DNMT3A.
  • Immunogen:
  • Recombinant protein corresponding to full length human DNMT3A.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 102
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunoprecipitation (2-4 ug/mg protein lysate)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 2 to 8°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with DNMT3A monoclonal antibody, clone PCRP-DNMT3A-1E2 (Cat # MAB20913).
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1788
  • Gene Name:
  • DNMT3A
  • Gene Alias:
  • DNMT3A2,M.HsaIIIA
  • Gene Description:
  • DNA (cytosine-5-)-methyltransferase 3 alpha
  • Gene Summary:
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • DNA MTase HsaIIIA,DNA cytosine methyltransferase 3 alpha,DNA cytosine methyltransferase 3A2,DNA methyltransferase HsaIIIA,OTTHUMP00000120005,OTTHUMP00000120006
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