CREB1 (phospho S133) monoclonal antibody, clone 4D11
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of SK-N-MC cell lysate with CREB1 (phospho S133) monoclonal antibody, clone 4D11 (Cat # MAB18872). Lane 1: untreated or Lane 2: treated with forskolin and IBMX.
Flow Cytometry
Flow cytometric analysis of SK-N-MC cells with CREB1 (phospho S133) monoclonal antibody, clone 4D11 (Cat # MAB18872). Secondary antibody only negative control (blue) or untreated (red) or treated with Forskolin (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human CREB1.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S133 of human CREB1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of SK-N-MC cell lysate with CREB1 (phospho S133) monoclonal antibody, clone 4D11 (Cat # MAB18872). Lane 1: untreated or Lane 2: treated with forskolin and IBMX.Flow Cytometry
Flow cytometric analysis of SK-N-MC cells with CREB1 (phospho S133) monoclonal antibody, clone 4D11 (Cat # MAB18872). Secondary antibody only negative control (blue) or untreated (red) or treated with Forskolin (green). -
Gene Info — CREB1
Entrez GeneID
1385Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
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Interactome
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Pathway
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Disease
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