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Last updated: 2017/12/10
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TIMP1 monoclonal antibody, clone 2A5

  • Catalog # : MAB1799
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of TIMP1.
  • Immunogen:
  • A synthetic peptide corresponding to human TIMP1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Monkey
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of TIMP1 expression in TIMP1 monoclonal antibody, clone 2A5 (Cat # MAB1799) against recombinant human TIMP1 proenzyme (400 ng lane).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of TIMP1 on human colon carcinoma tissue with TIMP1 monoclonal antibody, clone 2A5 (Cat # MAB1799).
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7076
  • Gene Name:
  • TIMP1
  • Gene Alias:
  • CLGI,EPA,EPO,FLJ90373,HCI,TIMP
  • Gene Description:
  • TIMP metallopeptidase inhibitor 1
  • Gene Summary:
  • This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023214,erythroid potentiating activity,fibroblast collagenase inhibitor,tissue inhibitor of metalloproteinase 1
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