TIMP1 monoclonal antibody, clone 24g0s
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant TIMP1.
Immunogen
Recombinant protein corresponding to full length human TIMP1.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes recombinant protein TIMP1.
Form
Liquid
Purification
Affinity purification
Concentration
1 ug/uL
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis in TIMP1 recombinant protein with TIMP1 monoclonal antibody, clone 24g0s (Cat # MAB8786) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TIMP1
Entrez GeneID
7076Protein Accession#
NM_003254.2Gene Name
TIMP1
Gene Alias
CLGI, EPA, EPO, FLJ90373, HCI, TIMP
Gene Description
TIMP metallopeptidase inhibitor 1
Omim ID
305370Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq
Other Designations
OTTHUMP00000023214|erythroid potentiating activity|fibroblast collagenase inhibitor|tissue inhibitor of metalloproteinase 1
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