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GUCY1A3 monoclonal antibody, clone 3G6B2 

  • Catalog # : MAB17805
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human GUCY1A3.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 22-214 of human GUCY1A3 from E. coli.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 77.5
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Immunocytochemistry (1:200-1:1000)
    Immunohistochemistry (1:200-1:1000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of (1) HEK293 cell, (2) Jurkat cell with GUCY1A3 monoclonal antibody.
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of (1) HEK293 cells, (2) GUCY1A3-hIgGFc transfected HEK293 cell lysate with GUCY1A3 monoclonal antibody.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded esophageal cancer tissue with GUCY1A3 monoclonal antibody.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HepG2 cells with GUCY1A3 monoclonal antibody (green). DRAQ5 fluorescent DNA dye (blue). Actin filaments labeled with Alexa Fluor-555 phalloidin (red).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis of GUCY1A3 monoclonal antibody, clone 3G6B2.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HEK293 cells with GUCY1A3 monoclonal antibody (green) and negative control (purple).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2982
  • Gene Name:
  • GUCY1A3
  • Gene Alias:
  • GC-SA3,GUC1A3,GUCA3,GUCSA3,GUCY1A1
  • Gene Description:
  • guanylate cyclase 1, soluble, alpha 3
  • Gene Summary:
  • Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM
  • Other Designations:
  • GC-S-alpha-1,soluble guanylate cyclase large subunit
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