NTRK2 monoclonal antibody, clone 10B6C4
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More Files
- More Functions
Western Blot
Western Blot analysis of (1) HEK293 cells, (2) NTRK2-hIgGFc transfected HEK293 cell lysate.
Western Blot
Western Blot analysis of human NTRK2 recombinant protein.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of breast cancer tissues with DAB staining.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of NTRK2 monoclonal antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human NTRK2.
Immunogen
Recombinant protein corresponding to amino acids 207-339 of of human NTRK2 from E. coli.
Host
Mouse
Theoretical MW (kDa)
92
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of (1) HEK293 cells, (2) NTRK2-hIgGFc transfected HEK293 cell lysate.Western Blot
Western Blot analysis of human NTRK2 recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of breast cancer tissues with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of NTRK2 monoclonal antibody. -
Gene Info — NTRK2
Entrez GeneID
4915Gene Name
NTRK2
Gene Alias
GP145-TrkB, TRKB
Gene Description
neurotrophic tyrosine kinase, receptor, type 2
Omim ID
600456Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BDNF/NT-3 growth factors receptor|OTTHUMP00000021573|OTTHUMP00000021574|OTTHUMP00000021575|OTTHUMP00000021576|OTTHUMP00000021577|tyrosine kinase receptor B
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Interactome
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Pathway
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Disease
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