NTRK2 recombinant monoclonal antibody, clone R04-3D9
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More Files
- More Functions
Western Blot
Western blot analysis of Phospho-TrkA (tyr490)/TrkB (Tyr516) in K562, C6, 3T3 lysates using human Phospho-TrkA/B (Tyr490/Tyr516) recombinant monoclonal antibody, clone R04-3D9 (Cat # RAB01675).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic phosphopeptide corresponding to residues surrounding Tyr516 of human TrkB.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Tyr516 of human TrkB
Theoretical MW (kDa)
Calculated MW: 92 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Phospho-TrkA (tyr490)/TrkB (Tyr516) in K562, C6, 3T3 lysates using human Phospho-TrkA/B (Tyr490/Tyr516) recombinant monoclonal antibody, clone R04-3D9 (Cat # RAB01675). -
Gene Info — NTRK2
Entrez GeneID
4915Protein Accession#
Q16620Gene Name
NTRK2
Gene Alias
GP145-TrkB, TRKB
Gene Description
neurotrophic tyrosine kinase, receptor, type 2
Omim ID
600456Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BDNF/NT-3 growth factors receptor|OTTHUMP00000021573|OTTHUMP00000021574|OTTHUMP00000021575|OTTHUMP00000021576|OTTHUMP00000021577|tyrosine kinase receptor B
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Disease
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