NTRK2 (Phospho Y705) recombinant monoclonal antibody
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NTRK2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Tyr705 of human NTRK2.
Theoretical MW (kDa)
80150
Reactivity
Human, Rat
Specificity
Recognizes endogenous levels of TRK B (pY705) protein.
Form
Liquid
Purification
Immunogen affinity chromatography
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
Storage Buffer
In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Hela (A), A549 (B), C6 (C) whole cell lysates with NTRK2 (Phospho Y705) recombinant monoclonal antibody (Cat # RAB02574). -
Gene Info — NTRK2
Entrez GeneID
4915Protein Accession#
Q16620Gene Name
NTRK2
Gene Alias
GP145-TrkB, TRKB
Gene Description
neurotrophic tyrosine kinase, receptor, type 2
Omim ID
600456Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BDNF/NT-3 growth factors receptor|OTTHUMP00000021573|OTTHUMP00000021574|OTTHUMP00000021575|OTTHUMP00000021576|OTTHUMP00000021577|tyrosine kinase receptor B
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