SLC17A7 monoclonal antibody, clone CL2754
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human SLC17A7.
Immunogen
Recombinant protein corresponding to human SLC17A7.
Epitope
This antibody binds to an epitope located within the peptide sequence EERKYIEDAI as determined by overlapping synthetic peptides.
Sequence
PSISEEERKYIEDAIGESAKLMNPLTKFSTP
Host
Mouse
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Protein A purification
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:5000-1:10000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human cerebral cortex tissue lysate with SLC17A7 monoclonal antibody, clone CL2754 (Cat # MAB15771).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with SLC17A7 monoclonal antibody, clone CL2754 (Cat # MAB15771) shows strong immunoreactivity in neuropil. -
Gene Info — SLC17A7
Entrez GeneID
57030Protein Accession#
Q9P2U7Gene Name
SLC17A7
Gene Alias
BNPI, VGLUT1
Gene Description
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
Omim ID
605208Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq
Other Designations
brain-specific Na-dependent inorganic phosphate cotransporter|solute carrier family 17, member 7|vesicular glutamate transporter 1
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