DES monoclonal antibody, clone RM234
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against of human DES.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to internal region of human DES.
Sequence
N/A
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:4000)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse heart tissue lysates with DES monoclonal antibody, clone RM234 (Cat # MAB15124) at a 1: 1,000 dilution, showed a band of DES (~54 kDa) expressed in mouse heart.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart with DES monoclonal antibody, clone RM234 (Cat # MAB15124) at 1:4000 dilution. -
Gene Info — DES
Entrez GeneID
1674Protein Accession#
P17661Gene Name
DES
Gene Alias
CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Gene Description
desmin
Gene Ontology
HyperlinkGene Summary
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
Other Designations
OTTHUMP00000064865|intermediate filament protein
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Interactome
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Disease
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