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Caldesmon monoclonal antibody, clone hHCD

  • Catalog # : MAB1430
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length native human caldesmon.
  • Immunogen:
  • Native purified caldesmon from human uterus smooth muscle.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rabbit
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (2-4 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (1.2% sodium acetate, 2 mg BSA, 0.01mg sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 800
  • Gene Name:
  • CALD1
  • Gene Alias:
  • CDM,H-CAD,L-CAD,MGC21352,NAG22
  • Gene Description:
  • caldesmon 1
  • Gene Summary:
  • This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
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