CALD1 recombinant monoclonal antibody, clone R05-3D2
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More Files
- More Functions
Western Blot
Western blot analysis of CALD1 in C6, 3T3, Hela lysates using human Caldesmon recombinant monoclonal antibody, clone R05-3D2 (Cat # RAB01546).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Human colon cancer with Caldesmon recombinant monoclonal antibody, clone R05-3D2 (Cat # RAB01546).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Caldesmon.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Caldesmon
Theoretical MW (kDa)
Calculated MW: 93 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1/100)
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of CALD1 in C6, 3T3, Hela lysates using human Caldesmon recombinant monoclonal antibody, clone R05-3D2 (Cat # RAB01546).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Human colon cancer with Caldesmon recombinant monoclonal antibody, clone R05-3D2 (Cat # RAB01546).Immunoprecipitation
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Gene Info — CALD1
Entrez GeneID
800Protein Accession#
Q05682Gene Name
CALD1
Gene Alias
CDM, H-CAD, L-CAD, MGC21352, NAG22
Gene Description
caldesmon 1
Omim ID
114213Gene Ontology
HyperlinkGene Summary
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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