CD55 monoclonal antibody, clone JS11 (FITC)
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More Files
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Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with CD55 monoclonal antibody, clone JS11 (FITC) (Cat # MAB13712).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human CD55.
Immunogen
Recombinant protein corresponding to full length human CD55.
Host
Mouse
Theoretical MW (kDa)
60-70
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Protein A/G purification
Purity
>90%
Isotype
IgG1
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with CD55 monoclonal antibody, clone JS11 (FITC) (Cat # MAB13712). -
Gene Info — CD55
Entrez GeneID
1604Protein Accession#
P08174Gene Name
CD55
Gene Alias
CR, CROM, DAF, TC
Gene Description
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Omim ID
125240Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD55 antigen|decay accelerating factor for complement
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Interactome
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Pathway
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Disease
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