CD55 recombinant monoclonal antibody, clone 1A5
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CD55.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human CD55.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: A549 whole cell lysate; Lane 2: 293T whole cell lysate; Lane 3: K562 whole cell lysate.Immunohistochemistry
Immunohistochemistry image of CD55 recombinant monoclonal antibody, clone 1A5 diluted at 1:100 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD55
Entrez GeneID
1604Protein Accession#
P08174Gene Name
CD55
Gene Alias
CR, CROM, DAF, TC
Gene Description
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Omim ID
125240Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD55 antigen|decay accelerating factor for complement
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Interactome
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Pathway
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Disease
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