LAT monoclonal antibody, clone LAT1111
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of human PBMC with LAT monoclonal antibody, clone LAT1111 (Cat # MAB12960) followed by HRP-conjugated goat anti-mouse secondary antibody and visualized by chemiluminescence detection system.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with LAT monoclonal antibody, clone LAT1111 (Cat # MAB12960) at 10 ug/mL working concentration.
-
Specification
Product Description
Mouse monoclonal antibody raised against recombinant human LAT.
Immunogen
Recombinant protein corresponding to cytoplasmic domain of human LAT.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide).
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western Blot analysis of human PBMC with LAT monoclonal antibody, clone LAT1111 (Cat # MAB12960) followed by HRP-conjugated goat anti-mouse secondary antibody and visualized by chemiluminescence detection system.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with LAT monoclonal antibody, clone LAT1111 (Cat # MAB12960) at 10 ug/mL working concentration.Immunoprecipitation
-
Gene Info — LAT
Entrez GeneID
27040Protein Accession#
O43561Gene Name
LAT
Gene Alias
LAT1, pp36
Gene Description
linker for activation of T cells
Omim ID
602354Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
36 kDa phospho-tyrosine adaptor protein
-
Interactome
-
Pathway
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com