IL17A monoclonal antibody, clone 4K5F6
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of Lane 1: human, Lane 2: mouse and Lane 3: rat full-length IL17A recombinant protein with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) at 0.2 ug/mL working concentration.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small intestine with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) at 5-10 ug/mL working concentration.
Flow Cytometry
Flow cytometric analysis of human lymphocytes with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) (red histogram) and an isotype control (green histogram) followed by FITC-conjugated goat anti-mouse IgG as the secondary antibody.
-
Specification
Product Description
Mouse monoclonal antibody raised against human IL17A.
Immunogen
A peptide corresponding to amino acids 1-75 of human IL17A.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
Western Blot (0.2-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Recombinant protein)
Western blot analysis of Lane 1: human, Lane 2: mouse and Lane 3: rat full-length IL17A recombinant protein with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) at 0.2 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small intestine with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) at 5-10 ug/mL working concentration.Flow Cytometry
Flow cytometric analysis of human lymphocytes with IL17A monoclonal antibody, clone 4K5F6 (Cat # MAB12727) (red histogram) and an isotype control (green histogram) followed by FITC-conjugated goat anti-mouse IgG as the secondary antibody. -
Gene Info — IL17A
Entrez GeneID
3605Gene Name
IL17A
Gene Alias
CTLA8, IL-17, IL-17A, IL17
Gene Description
interleukin 17A
Omim ID
603149Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000016597|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|cytotoxic T-lymphocyte-associated serine esterase 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com