Western blot analysis of Lane 1: Jurkat whole cell lysates Lane 2: MCF-7 whole cell lysates Lane 3: K562 whole cell lysates Lane 4: A549 whole cell lysates Lane 5: mouse NIH/3T3 cell line lysates reacted with RPS6KB2 monoclonal antibody (Cat # MAB12306) at 1:1000 dilution.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq