RPS6KB2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RPS6KB2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of RPS6KB2 polyclonal antibody (Cat # PAB3203) in A-375 cell lysate. RPS6KB2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. -
Gene Info — RPS6KB2
Entrez GeneID
6199Protein Accession#
NP_001007072;Q9UBS0Gene Name
RPS6KB2
Gene Alias
KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb
Gene Description
ribosomal protein S6 kinase, 70kDa, polypeptide 2
Omim ID
608939Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq
Other Designations
S6 kinase-related kinase|p70 ribosomal S6 kinase beta|ribosomal protein S6 kinase, 70kD, polypeptide 2|serine/threonine-protein kinase 14 beta
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Interactome
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Disease
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Publication Reference
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S6 kinase 2 potentiates interleukin-3-driven cell proliferation.
Cruz R, Hedden L, Boyer D, Kharas MG, Fruman DA, Lee-Fruman KK.
Journal of Leukocyte Biology 2005 Oct; 78(6):1378.
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S6 kinase 2 potentiates interleukin-3-driven cell proliferation.
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