RPS6KB2 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human RPS6KB2 protein.
Immunogen
RPS6KB2 (AAH06106.3, 1 a.a. ~ 482 a.a) full-length human protein.
Sequence
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RPS6KB2 expression in transfected 293T cell line (H00006199-T01) by RPS6KB2 MaxPab polyclonal antibody.
Lane 1: RPS6KB2 transfected lysate(53.02 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RPS6KB2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RPS6KB2
Entrez GeneID
6199GeneBank Accession#
BC006106.1Protein Accession#
AAH06106.3Gene Name
RPS6KB2
Gene Alias
KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb
Gene Description
ribosomal protein S6 kinase, 70kDa, polypeptide 2
Omim ID
608939Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq
Other Designations
S6 kinase-related kinase|p70 ribosomal S6 kinase beta|ribosomal protein S6 kinase, 70kD, polypeptide 2|serine/threonine-protein kinase 14 beta
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Interactomes
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Pathways
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Diseases
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Publication Reference
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S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells.
Warner MJ, Bridge KS, Hewitson JP, Hodgkinson MR, Heyam A, Massa BC, Haslam JC, Chatzifrangkeskou M, Evans GJ, Plevin MJ, Sharp TV, Lagos D.
Nucleic Acids Research 2016 Nov; 44(20):9942.
Application:PLA, Human, Dermal lymphatic endothelial cells.
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S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells.
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