NKX3-1 monoclonal antibody, clone 4H4
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant NKX3-1.
Immunogen
Recombinant protein corresponding to human NKX3-1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using NKX3-1 monoclonal antibody, clone 4H4 (Cat # MAB10832) against LNCaP cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver tissues using NKX3-1 monoclonal antibody, clone 4H4 (Cat # MAB10832).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human prostate tissues (A, B) using NKX3-1 monoclonal antibody, clone 4H4 (Cat # MAB10832) with DAB staining.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometric analysis of PC-3 cells using NKX3-1 monoclonal antibody, clone 4H4 (Cat # MAB10832) (green) and negative control (purple). -
Gene Info — NKX3-1
Entrez GeneID
4824Gene Name
NKX3-1
Gene Alias
BAPX2, NKX3, NKX3.1, NKX3A
Gene Description
NK3 homeobox 1
Omim ID
602041Gene Ontology
HyperlinkGene Summary
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM
Other Designations
NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|OTTHUMP00000123534
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