NKX3-1 monoclonal antibody, clone RM430
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NKX3-1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to the N-terminus of human NKX3-1.
Reactivity
Human
Specificity
This antibody reacts to human NKX3-1.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunochemistry (1:100 - 1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human prostate cancer tissue section using NKX3-1 monoclonal antibody clone RM430 at a 1:200 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human prostate section using NKX3-1 monoclonal antibody clone RM430 at a 1:200 dilution. -
Gene Info — NKX3-1
Entrez GeneID
4824Gene Name
NKX3-1
Gene Alias
BAPX2, NKX3, NKX3.1, NKX3A
Gene Description
NK3 homeobox 1
Omim ID
602041Gene Ontology
HyperlinkGene Summary
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM
Other Designations
NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|OTTHUMP00000123534
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