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Last updated: 2017/11/19

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GPC3 monoclonal antibody, clone 1G12

  • Catalog # : MAB10762
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against GPC3.
  • Immunogen:
  • GPC3.
  • Host:
  • Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Positive control use as hepatocellular carcinoma (HCC).
    Visualization at cytoplasmic.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (protein base, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C is stable for 3 years.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Application Image
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 2719
  • Gene Name:
  • GPC3
  • Gene Alias:
  • DGSX,OCI-5,SDYS,SGB,SGBS,SGBS1
  • Gene Description:
  • glypican 3
  • Gene Summary:
  • Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024058,OTTHUMP00000062492,glypican proteoglycan 3
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