GPC3 recombinant monoclonal antibody, clone GPC3/1534R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against a partial human Glypican-3 protein.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to a partial human Glypican-3 protein
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Concentration
0.2 mg/mL
Isotype
IgG
Recommend Usage
Flow cytometry (0.5-1ug/10e6 cells in 0.1mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(0.5-1 ug/mL for 30 min at RT)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage Instruction
Store at 2~8°C.
Aliquot to avoid repeated freezing and thawing.Note
Optimal dilutions for each application to be determined by the researcher
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human fetal liver tissue with anti-Glypican-3 recombinant monoclonal antibody, clone GPC3/1534R (Cat # RAB03817).Immunofluorescence
Flow Cytometry
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Gene Info — GPC3
Entrez GeneID
2719Protein Accession#
P51654Gene Name
GPC3
Gene Alias
DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1
Gene Description
glypican 3
Gene Ontology
HyperlinkGene Summary
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000024058|OTTHUMP00000062492|glypican proteoglycan 3
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