CDC37 monoclonal antibody (M01), clone 3C7
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More Files
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Western Blot (Cell lysate)
CDC37 monoclonal antibody (M01), clone 3C7. Western Blot analysis of CDC37 expression in HL-60 ( Cat # L014V1 ).
Western Blot (Transfected lysate)
Western Blot analysis of CDC37 expression in transfected 293T cell line by CDC37 monoclonal antibody (M01), clone 3C7.
Lane 1: CDC37 transfected lysate(44.5 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CDC37 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 1 ug/ml]
Immunofluorescence
Immunofluorescence of monoclonal antibody to CDC37 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (67.32 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CDC37.
Immunogen
CDC37 (AAH08793.1, 1 a.a. ~ 378 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MMDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKIADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHVQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (92)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (67.32 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CDC37 monoclonal antibody (M01), clone 3C7. Western Blot analysis of CDC37 expression in HL-60 ( Cat # L014V1 ).Western Blot (Transfected lysate)
Western Blot analysis of CDC37 expression in transfected 293T cell line by CDC37 monoclonal antibody (M01), clone 3C7.
Lane 1: CDC37 transfected lysate(44.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CDC37 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 1 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CDC37 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — CDC37
Entrez GeneID
11140GeneBank Accession#
BC008793Protein Accession#
AAH08793.1Gene Name
CDC37
Gene Alias
P50CDC37
Gene Description
cell division cycle 37 homolog (S. cerevisiae)
Omim ID
605065Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq
Other Designations
CDC37 (cell division cycle 37, S. cerevisiae, homolog)|CDC37 cell division cycle 37 homolog|Hsp90 co-chaperone Cdc37|cell division cycle 37 protein
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Interactome
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Disease
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