CDC37 recombinant monoclonal antibody, clone 10C3
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: Hela whole cell lysate; Lane 2: Jurkat whole cell lysate; Lane 3: MCF-7 whole cell lysate; Lane 4: 293 whole cell lysate; Lane 5: K562 whole cell lysate; Lane 6: PC-3 whole cell lysate.
Flow Cytometry
Overlay histogram showing Hela cells stained with CDC37 recombinant monoclonal antibody, clone 10C3 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CDC37.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human CDC37.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry (1:20-1:200)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: Hela whole cell lysate; Lane 2: Jurkat whole cell lysate; Lane 3: MCF-7 whole cell lysate; Lane 4: 293 whole cell lysate; Lane 5: K562 whole cell lysate; Lane 6: PC-3 whole cell lysate.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay histogram showing Hela cells stained with CDC37 recombinant monoclonal antibody, clone 10C3 (red line) at 1:50. -
Gene Info — CDC37
Entrez GeneID
11140Protein Accession#
Q16543Gene Name
CDC37
Gene Alias
P50CDC37
Gene Description
cell division cycle 37 homolog (S. cerevisiae)
Omim ID
605065Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq
Other Designations
CDC37 (cell division cycle 37, S. cerevisiae, homolog)|CDC37 cell division cycle 37 homolog|Hsp90 co-chaperone Cdc37|cell division cycle 37 protein
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Interactome
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Disease
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