TNFRSF11A (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TNFRSF11A partial ORF ( NP_003830, 31 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
APPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (79); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TNFRSF11A
Entrez GeneID
8792GeneBank Accession#
NM_003839Protein Accession#
NP_003830Gene Name
TNFRSF11A
Gene Alias
CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Gene Description
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells. [provided by RefSeq
Other Designations
loss of heterozygosity, 18, chromosomal region 1|osteoclast differentiation factor receptor|receptor activator of nuclear factor-kappa B|tumor necrosis factor receptor superfamily, member 11a|tumor necrosis factor receptor superfamily, member 11a, activat
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Interactome
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