HSD17B6 purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human HSD17B6 protein.
Immunogen
HSD17B6 (NP_003716.2, 1 a.a. ~ 317 a.a) full-length human protein.
Sequence
MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTSLADYILTRSWPKPAQAV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HSD17B6 MaxPab polyclonal antibody. Western Blot analysis of HSD17B6 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of HSD17B6 expression in transfected 293T cell line (H00008630-T01) by HSD17B6 MaxPab polyclonal antibody.
Lane 1: HSD17B6 transfected lysate(34.87 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HSD17B6
Entrez GeneID
8630GeneBank Accession#
NM_003725.2Protein Accession#
NP_003716.2Gene Name
HSD17B6
Gene Alias
HSE, RODH, SDR9C6
Gene Description
hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
Omim ID
606623Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq
Other Designations
3(alpha->beta)-hydroxysteroid epimerase|3(alpha->beta)-hydroxysteroid epimerasel|3-hydroxysteroid epimerase|NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase|hydroxysteroid (17-beta) dehydrogenase 6|oxidative 3-alpha-hydroxys
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Interactomes
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Diseases
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