HSD17B6 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human HSD17B6 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — HSD17B6
Entrez GeneID
8630GeneBank Accession#
NM_003725.2Protein Accession#
NP_003716.2Gene Name
HSD17B6
Gene Alias
HSE, RODH, SDR9C6
Gene Description
hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
Omim ID
606623Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq
Other Designations
3(alpha->beta)-hydroxysteroid epimerase|3(alpha->beta)-hydroxysteroid epimerasel|3-hydroxysteroid epimerase|NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase|hydroxysteroid (17-beta) dehydrogenase 6|oxidative 3-alpha-hydroxys
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Interactome
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Disease
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