HSD17B6 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HSD17B6 full-length
Host
Human
Theoretical MW (kDa)
34.98
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HSD17B6 antibody (H00008630-B01) by Western Blots.
SDS-PAGE Gel
HSD17B6 transfected lysate.
Western Blot
Lane 1: HSD17B6 transfected lysate ( 34.98 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HSD17B6
Entrez GeneID
8630GeneBank Accession#
NM_003725.2Protein Accession#
NP_003716.2Gene Name
HSD17B6
Gene Alias
HSE, RODH, SDR9C6
Gene Description
hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
Omim ID
606623Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq
Other Designations
3(alpha->beta)-hydroxysteroid epimerase|3(alpha->beta)-hydroxysteroid epimerasel|3-hydroxysteroid epimerase|NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase|hydroxysteroid (17-beta) dehydrogenase 6|oxidative 3-alpha-hydroxys
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Interactome
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Disease
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