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Last updated: 2016/10/23
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SPOP purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00008405-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human SPOP protein.
  • Immunogen:
  • SPOP (NP_001007227.1, 1 a.a. ~ 374 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SPOP expression in transfected 293T cell line (H00008405-T01) by SPOP MaxPab polyclonal antibody.

    Lane 1: SPOP transfected lysate(41.14 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Entrez GeneID:
  • 8405
  • Gene Name:
  • SPOP
  • Gene Alias:
  • TEF2
  • Gene Description:
  • speckle-type POZ protein
  • Gene Summary:
  • This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • -
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