SPOP monoclonal antibody (M04), clone 3E2
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SPOP is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (33.88 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SPOP.
Immunogen
SPOP (NP_001007227.1, 301 a.a. ~ 374 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.88 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SPOP is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — SPOP
Entrez GeneID
8405GeneBank Accession#
NM_001007226Protein Accession#
NP_001007227.1Gene Name
SPOP
Gene Alias
TEF2
Gene Description
speckle-type POZ protein
Omim ID
602650Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
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Interactome
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Disease
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