WHSC2 purified MaxPab mouse polyclonal antibody (B03P)
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More Files
- More Functions
Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in NIH/3T3.
Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in Hela S3 NE.
Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in Raw 264.7.
Western Blot (Transfected lysate)
Western Blot analysis of WHSC2 expression in transfected 293T cell line (H00007469-T02) by WHSC2 MaxPab polyclonal antibody.
Lane 1: WHSC2 transfected lysate(58.08 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to WHSC2 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human WHSC2 protein.
Immunogen
WHSC2 (NP_005654.2, 1 a.a. ~ 528 a.a) full-length human protein.
Sequence
MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHGLSSAVKLKLLLGTLHLPRRTVDEMKGALMEIIQLASLDSDPWVLMVADILKSFPDTGSLNLELEEQNPNVQDILGELREKVGECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTAPSVFSPTGNRTPIPPSRTLLRKERGVKLLDISELDMVGAGREAKRRRKTLDAEVVEKPAKEETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPSTPSVVPASSYIPSSETPPAPSSREASRPPEEPSAPSPTLPAQFKQRAPMYNSGLSPATPTPAAPTSPLTPTTPPAVAPTTQTPPVAMVAPQTQAPAQQQPKKNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCQEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNVS
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in NIH/3T3.Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in Hela S3 NE.Western Blot (Cell lysate)
WHSC2 MaxPab polyclonal antibody. Western Blot analysis of WHSC2 expression in Raw 264.7.Western Blot (Transfected lysate)
Western Blot analysis of WHSC2 expression in transfected 293T cell line (H00007469-T02) by WHSC2 MaxPab polyclonal antibody.
Lane 1: WHSC2 transfected lysate(58.08 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to WHSC2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — WHSC2
Entrez GeneID
7469GeneBank Accession#
NM_005663.2Protein Accession#
NP_005654.2Gene Name
WHSC2
Gene Alias
FLJ10442, FLJ25112, NELF-A, NELFA, P/OKcl.15
Gene Description
Wolf-Hirschhorn syndrome candidate 2
Omim ID
606026Gene Ontology
HyperlinkGene Summary
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq
Other Designations
Wolf-Hirschhorn syndrome candidate 2 protein
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Interactome
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Disease
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